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Government Grants in California

3,571 state-specific grants + 3,334 federal programs available in California.

California offers one of the most robust grant ecosystems in the country, with state programs from CalOSBA, GO-Biz, and dozens of agency-specific funding opportunities alongside federal grants. The state administers SSBCI programs for small business lending, CalRecycle grants for environmental projects, and numerous workforce development initiatives.

Business & Commerce

SSBCI Loan Guarantee Program — California

U.S. Department of the Treasury

Amount varies
Business & Commerce

SSBCI CAP Program — California

U.S. Department of the Treasury

Amount varies
Business & Commerce

SSBCI Collateral Support Program — California

U.S. Department of the Treasury

Amount varies
Science & Technology

Purpose is to Provide a No Cost Schedule Extension and Extend the Period of Performance From August 30, 2024 to November 30, 2024. As a Result Article(S) C.1., F.1. and G.3. Needs to Be Updated

Department of Health and Human Services — National Institutes of Health

Up to $455K
Science & Technology

Sbir Fy25 Concept Award: Targeting Dysfunctional Chromatin Networks in Dipg

Department of Health and Human Services — National Institutes of Health

Up to $355K
Science & Technology

Soft Low-Cost Additively Manufactured Bionic Arm Prosthetic.

Department of Health and Human Services — Administration for Community Living

Up to $100K
Science & Technology

Topic Number: Arpa-H 05: Scale-Up: Transition Disruptive Technologies From Proof-of-Concept Prototypes to Commercially Scalable and Deployable Technologies

Department of Health and Human Services — National Institutes of Health

Up to $3.5M
Science & Technology

Development of Rabbit Monoclonal Antibodies for Indian Flying Fox (Bat) Biomarkers

Department of Health and Human Services — National Institutes of Health

Up to $593K
Science & Technology

An Antigen-Based Rapid Test to detect L. loa infections, Aimed at Supporting Onchocerciasis Elimination Programs

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Multiplexed Nucleic Acid Self-Test for Reproducible and Sensitive Hiv Detection

Department of Health and Human Services — National Institutes of Health

Up to $595K
Science & Technology

A Miniaturized Ad Mps Platform for High-Throughput Drug Screening

Department of Health and Human Services — National Institutes of Health

Up to $500K
Science & Technology

Development of a VesiVax TLR7 Formula as an Effective Adjuvant

Department of Health and Human Services — National Institutes of Health

Up to $3.0M
Science & Technology

CRISPR-based Assay for Portable Tropical Infection Diagnosis (CAPTIN-D)

Department of Health and Human Services — National Institutes of Health

Up to $1.5M
Science & Technology

Neurometric Authentication for Secure and Real-Time Access Management in Healthcare Environments

Department of Health and Human Services — National Institutes of Health

Up to $599K
Science & Technology

Topic 455: Ideal at-Home Prostate Specific Antigen (Psa) Testing

Department of Health and Human Services — National Institutes of Health

Up to $390K
Science & Technology

Affinity Reagents for the Immune System of Guinea Pigs Il1b, Il2, Il4, Il6, Il8, Il10, Il12, and Il13.

Department of Health and Human Services — National Institutes of Health

Up to $1.5M
Science & Technology

Topic 455: Fingerstick Blood Test for Point-of-Care Detection of Prostate Specific Antigen

Department of Health and Human Services — National Institutes of Health

Up to $383K
Science & Technology

Development of Snow Cleaning With Supercritical Co2

Department of Health and Human Services — National Institutes of Health

Up to $325K
Science & Technology

Engineered Microbial Therapeutics for Methionine Restriction Treatment of Heritable Forms of Glioma.

Department of Health and Human Services — National Institutes of Health

Up to $355K
Science & Technology

Lotus Ring: Wearable Technology for Independence at Home - Pilot

Department of Health and Human Services — Administration for Community Living

Up to $100K
Science & Technology

Fy2025 Sbir Concept Clearance Award or Topic Development of Therapeutic or Preventative Technologies for Treatment or Prevention of Pediatric Cancers and/or Rare Cancers

Department of Health and Human Services — National Institutes of Health

Up to $355K
Science & Technology

The Purpose of This Modification is to Exercise the I-Corp Option

Department of Health and Human Services — National Institutes of Health

Up to $355K
Science & Technology

""multiplexed Droplet Digital Nucleic Acid Amplification Technologies for Hiv Diagnosis""

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Phase I Award - an Organ-on-Vascularnet Model for in Vitro Evaluation of Radiation and Drug Therapies

Department of Health and Human Services — National Institutes of Health

Up to $400K
Science & Technology

Depth-Resolved Algal Bloom Mapping at Lake Okeechobee, FL

Engineer Research and Development Center

Up to $96K1d left
Health

Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)

National Institutes of Health

Up to $100K2d left
Income Security & Social Services

Support for a National Electronic Interstate Records Exchange System

Administration for Children and Families - ACYF/CB

Up to $1.6M2d left
Health

Service Area Competition - Additional Area 1

Health Resources and Services Administration

Up to $1.6M2d left
Other

International Religious Freedom Fund (I-REFF) Emergency Assistance

Bureau of Democracy Human Rights and Labor

Up to $4.9M2d left
Environment

2025 South Florida Program

Environmental Protection Agency

Up to $1.0M2d left
Science & Technology

Request for Information – Mutually Beneficial Multidisciplinary Innovation Ecosystems

Dept of the Army -- Materiel Command

Amount varies3d left
Education

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)

National Institutes of Health

Up to $350K5d left
Humanities

BJA FY25 Smart Reentry Demonstration Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

BJA FY25 Strengthening Community Supervision Agency Operations Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

OJJDP FY 2026 Attorney General Alliance Child ID Kits Invitation to Apply

Office of Juvenile Justice Delinquency Prevention

Up to $10.0M5d left
Education

Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional)

National Institutes of Health

Amount varies6d left
Science & Technology

ROSES25: F.19 Collaborative Opportunities for Mentorship, Partnership and Academic Success in Science

NASA Headquarters

Amount varies6d left
Education

Next Gen STEM (NGS) NASA Aerospace Skilled Technical Workforce Hubs (NAS_Hub)

National Aeronautics and Space Administration

Up to $1.5M6d left
Other

Alumni Engagement Innovation Fund (AEIF) 2026: Strengthen U.S.–Kazakhstan Partnerships Through Alumni-Led Innovation

U.S. Mission to Kazakhstan

Up to $35K6d left
Law, Justice & Legal Services

Securing Convictions from Vetted and Special Unit Operations

U.S. Mission to Mexico

Up to $1.5M6d left
Natural Resources

2026 Atlantic Sea Scallop Research Set Aside Program

DOC NOAA - ERA Production

Amount varies9d left
Disaster Prevention & Relief

Department of the Interior (DOI), Office of Wildland Fire (OWF) - Slip-On Tanker Units

Interior Business Center

Up to $249K9d left
Arts

NEA Research Grants in the Arts, FY 2027

National Endowment for the Arts

Up to $100K9d left
Arts

NEA Research Labs, FY 2027

National Endowment for the Arts

Up to $300K9d left
Science & Technology

Innovations in Graduate Education (IGE) Program

U.S. National Science Foundation

Up to $1.0M11d left
Science & Technology

Deployed Warfighter Protection (DWFP) Program for the Protection of Deployed Military Personnel from Threats Posed by Arthropod Disease Vectors

ACC-APG-Detrick

Up to $975K11d left
Agriculture

Agriculture and Food Research Initiative Strengthening Agricultural Systems

National Institute of Food and Agriculture

Up to $10.0M12d left
Community Development

Fiscal Year (FY) 2026 AmeriCorps Seniors RSVP Competition

AmeriCorps

Amount varies12d left

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