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Government Grants in Pennsylvania

893 state-specific grants + 3,334 federal programs available in Pennsylvania.

Pennsylvania's DCED runs over 100 grant, loan, and tax incentive programs for businesses. The state actively administers SSBCI credit programs and offers workforce development grants alongside extensive federal funding opportunities.

Business & Commerce

SSBCI Loan Participation Program — Pennsylvania

U.S. Department of the Treasury

Amount varies
Business & Commerce

SSBCI Venture Capital Program — Pennsylvania

U.S. Department of the Treasury

Amount varies
Science & Technology

Phase I Therapeutic Award: Chimeric Nanoparticle Delivery of an Sarna-Based Cancer Vaccine for Familial Adenomatous Polyposis

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Emotional Intelligence Training Tools Helping People with Autism Spectrum Disorder (ASD) Build Emotional Intelligence Skills on Social Media that Transition to the Real World.

Department of Health and Human Services — Administration for Community Living

Up to $100K
Science & Technology

Topic Number: 464 Sbir Phase I Cloud-Based Multimodal Data Analysis Software for the Cancer Research Data Commons

Department of Health and Human Services — National Institutes of Health

Up to $400K
Science & Technology

Antibody Reagents for Immunologic Analysis of Under-Represented Mammalian Models

Department of Health and Human Services — National Institutes of Health

Up to $1.5M
Science & Technology

AWARD PINMED SBIR TOPIC #114 PHASE I- Device to Permit Continuous Self-Monitoring of Blood Oxygen Saturation During Activities of Daily Living for Individuals at Risk for Desaturation During Physical Exertion

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Combinations of Oral Antibiotics to Treat Syphilis

Department of Health and Human Services — National Institutes of Health

Up to $307K
Science & Technology

A Rapid Point of Care Test for the Detection of Antibodies to Measles and Rubella

Department of Health and Human Services — Centers for Disease Control and Prevention

Up to $244K
Science & Technology

Sbir Fy25 Concept Award, Development of an Immunotherapy for Ewing Sarcoma Using a Novel Murine Model

Department of Health and Human Services — National Institutes of Health

Up to $355K
Science & Technology

Sbir Fy25 Concept Award, Targeting Plod2 in Undifferentiated Pleomorphic Sarcoma

Department of Health and Human Services — National Institutes of Health

Up to $355K
Science & Technology

Screening for Tolerogenic Adjuvants to Enhance Antigen Specific Immunotherapy for Celiac Disease.

Department of Health and Human Services — National Institutes of Health

Up to $600K
Science & Technology

Reagents for Immunologic Analysis of Under-represented Mammalian Models

Department of Health and Human Services — National Institutes of Health

Up to $600K
Business & Commerce

Educational Improvement Tax Credit Program (EITC)

PA DCED

Amount varies
Business & Commerce

Opportunity Scholarship Tax Credit Program (OSTC)

PA DCED

Amount varies
State Program

Weatherization Assistance Program (WAP)

PA DCED

Amount varies
Community Development

Community Development Block Grant (CDBG)

PA DCED

Amount varies
State Program

Multimodal Transportation Fund

PA DCED

Amount varies
State Program

Act 47 Program Page

PA DCED

Amount varies
State Program

Strategic Management Planning Program

PA DCED

Amount varies
State Program

Abandoned Mine Drainage Abatement and Treatment Program (AMDATP)

PA DCED

Amount varies
State Program

Airport Land Development Zones (ALDZ)

PA DCED

Amount varies
Environment

Alternative and Clean Energy Program (ACE)

PA DCED

Amount varies
State Program

Appalachian Regional Commission (ARC)

PA DCED

Amount varies
Science & Technology

Depth-Resolved Algal Bloom Mapping at Lake Okeechobee, FL

Engineer Research and Development Center

Up to $96K1d left
Health

Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)

National Institutes of Health

Up to $100K2d left
Income Security & Social Services

Support for a National Electronic Interstate Records Exchange System

Administration for Children and Families - ACYF/CB

Up to $1.6M2d left
Health

Service Area Competition - Additional Area 1

Health Resources and Services Administration

Up to $1.6M2d left
Other

International Religious Freedom Fund (I-REFF) Emergency Assistance

Bureau of Democracy Human Rights and Labor

Up to $4.9M2d left
Environment

2025 South Florida Program

Environmental Protection Agency

Up to $1.0M2d left
Science & Technology

Request for Information – Mutually Beneficial Multidisciplinary Innovation Ecosystems

Dept of the Army -- Materiel Command

Amount varies3d left
Education

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)

National Institutes of Health

Up to $350K5d left
Humanities

BJA FY25 Smart Reentry Demonstration Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

BJA FY25 Strengthening Community Supervision Agency Operations Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

OJJDP FY 2026 Attorney General Alliance Child ID Kits Invitation to Apply

Office of Juvenile Justice Delinquency Prevention

Up to $10.0M5d left
Education

Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional)

National Institutes of Health

Amount varies6d left
Science & Technology

ROSES25: F.19 Collaborative Opportunities for Mentorship, Partnership and Academic Success in Science

NASA Headquarters

Amount varies6d left
Education

Next Gen STEM (NGS) NASA Aerospace Skilled Technical Workforce Hubs (NAS_Hub)

National Aeronautics and Space Administration

Up to $1.5M6d left
Other

Alumni Engagement Innovation Fund (AEIF) 2026: Strengthen U.S.–Kazakhstan Partnerships Through Alumni-Led Innovation

U.S. Mission to Kazakhstan

Up to $35K6d left
Law, Justice & Legal Services

Securing Convictions from Vetted and Special Unit Operations

U.S. Mission to Mexico

Up to $1.5M6d left
Natural Resources

2026 Atlantic Sea Scallop Research Set Aside Program

DOC NOAA - ERA Production

Amount varies9d left
Disaster Prevention & Relief

Department of the Interior (DOI), Office of Wildland Fire (OWF) - Slip-On Tanker Units

Interior Business Center

Up to $249K9d left
Arts

NEA Research Grants in the Arts, FY 2027

National Endowment for the Arts

Up to $100K9d left
Arts

NEA Research Labs, FY 2027

National Endowment for the Arts

Up to $300K9d left
Science & Technology

Innovations in Graduate Education (IGE) Program

U.S. National Science Foundation

Up to $1.0M11d left
Science & Technology

Deployed Warfighter Protection (DWFP) Program for the Protection of Deployed Military Personnel from Threats Posed by Arthropod Disease Vectors

ACC-APG-Detrick

Up to $975K11d left
Agriculture

Agriculture and Food Research Initiative Strengthening Agricultural Systems

National Institute of Food and Agriculture

Up to $10.0M12d left
Community Development

Fiscal Year (FY) 2026 AmeriCorps Seniors RSVP Competition

AmeriCorps

Amount varies12d left

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