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Government Grants in Massachusetts

1,741 state-specific grants + 3,334 federal programs available in Massachusetts.

Federal government grants are available to applicants in this state across all major categories including health, education, science, environment, and business development. Browse the listings below to find programs you may qualify for, and always verify eligibility on the official program website.

Business & Commerce

SSBCI CAP Program — Massachusetts

U.S. Department of the Treasury

Amount varies
Business & Commerce

SSBCI Loan Participation Program — Massachusetts

U.S. Department of the Treasury

Amount varies
Science & Technology

Fy24 Sbir Phase I Topic No. 459 Project Title: an Automated Screening Platform for Early Identification of Malnutrition in Cancer Patients

Department of Health and Human Services — National Institutes of Health

Up to $400K
Science & Technology

PhaseI_Innotechprecisionmedicine_CDC_NCEZID_031

Department of Health and Human Services — Centers for Disease Control and Prevention

Up to $244K
Science & Technology

Sbir Phase 1 (Nih/Nimh Topic 002 - Development of Novel in-Vitro and in-Vivo Models to Support Neurohiv Research)

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Vector-Based Delivery of Hiv Broadly Neutralizing Antibodies

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

CRISPR-Based in Vitro Diagnostic Device for Rapid Detection of Eukaryotic Pathogens

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Arpa-H O1 Sbir Phase Ii - Novel Telehealth Instruments for Assessing Pediatric Well-Being. Project Title: Digital Assessment of Children's Conditions Using Artificial Intelligence (""daccs Ai"")

Department of Health and Human Services — National Institutes of Health

Up to $3.5M
Science & Technology

Coupled Acoustical Wave Micropillar Detection of Drugs in Blood Postmortem

Department of Health and Human Services — National Institutes of Health

Up to $400K
Science & Technology

Development of Digital Satiorx, a Very Low Cost Remotely Controllable Disposable Microneedle Transdermal Drug Delivery Device Able to Deliver Any Liquid Fda Approved Transdermal Drug

Department of Health and Human Services — National Institutes of Health

Up to $3.5M
Science & Technology

Sbir Topic 463: Clinical Evaluation for Early Detection of Esophageal Cancer With a Novel Fluorescence Endoscope and Pegulicianine, a Novel Fluorescent Probe

Department of Health and Human Services — National Institutes of Health

Up to $399K
Science & Technology

Feasibility of the Cranial Remolding Orthosis with Notification Electronics (CROWNE)

Department of Health and Human Services — Administration for Community Living

Up to $575K
Science & Technology

Sbir New Award to Sky Park Labs, Llc

Department of Health and Human Services — National Institutes of Health

Up to $298K
Science & Technology

Novel Diagnostic Biomarker Discovery and Validation for Malaria

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

IVD device for Patient Immune Profiling and personalized treatment selection (PIP)

Department of Health and Human Services — National Institutes of Health

Up to $4.1M
Science & Technology

Award Sbir Topic #110 Phase Ii-Mri Myocardial Biopsy System

Department of Health and Human Services — National Institutes of Health

Up to $3.0M
Science & Technology

Nimh Sbir Phase I Topic 001- Point-of-Care Hiv Viral Load and Drug Adherence Assays

Department of Health and Human Services — National Institutes of Health

Up to $306K
Science & Technology

A Multi-Modal Remote Measurement Platform for Decentralized Clinical Trials

Department of Health and Human Services — National Institutes of Health

Up to $2.0M
Science & Technology

Fy2024 Sbir Concept Award: "the Frugal Tile: High-Performance Detector for the Picosecond Frontier"

Department of Health and Human Services — National Institutes of Health

Up to $353K
Science & Technology

Sbir Innovative Concept Award (Topic - Development of Devices or Diagnostics for Treatment, Detection and Diagnosis of Pediatric Cancers and/or Rare Cancers)

Department of Health and Human Services — National Institutes of Health

Up to $340K
Science & Technology

High-Dose and Sustained Delivery of Hiv-1 Broadly Neutralizing Antibodies Via Subcutaneous Injection of Hydrogel-Based Microparticle Formations

Department of Health and Human Services — National Institutes of Health

Up to $295K
Science & Technology

Point-of-Care Monitoring of Adherence to Antiretroviral Hiv Therapy

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

Topic Number 431 Cancer Treatment Technologies for Low-Resource Settings

Department of Health and Human Services — National Institutes of Health

Up to $2.0M
Science & Technology

Topic 455: a Low Cost, Point-of-Care Detection Device for Prostate Specific Antigen Using a Paper-Based Flow Assay

Department of Health and Human Services — National Institutes of Health

Up to $400K
Science & Technology

Depth-Resolved Algal Bloom Mapping at Lake Okeechobee, FL

Engineer Research and Development Center

Up to $96K1d left
Health

Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)

National Institutes of Health

Up to $100K2d left
Income Security & Social Services

Support for a National Electronic Interstate Records Exchange System

Administration for Children and Families - ACYF/CB

Up to $1.6M2d left
Health

Service Area Competition - Additional Area 1

Health Resources and Services Administration

Up to $1.6M2d left
Other

International Religious Freedom Fund (I-REFF) Emergency Assistance

Bureau of Democracy Human Rights and Labor

Up to $4.9M2d left
Environment

2025 South Florida Program

Environmental Protection Agency

Up to $1.0M2d left
Science & Technology

Request for Information – Mutually Beneficial Multidisciplinary Innovation Ecosystems

Dept of the Army -- Materiel Command

Amount varies3d left
Education

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)

National Institutes of Health

Up to $350K5d left
Humanities

BJA FY25 Smart Reentry Demonstration Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

BJA FY25 Strengthening Community Supervision Agency Operations Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

OJJDP FY 2026 Attorney General Alliance Child ID Kits Invitation to Apply

Office of Juvenile Justice Delinquency Prevention

Up to $10.0M5d left
Education

Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional)

National Institutes of Health

Amount varies6d left
Science & Technology

ROSES25: F.19 Collaborative Opportunities for Mentorship, Partnership and Academic Success in Science

NASA Headquarters

Amount varies6d left
Education

Next Gen STEM (NGS) NASA Aerospace Skilled Technical Workforce Hubs (NAS_Hub)

National Aeronautics and Space Administration

Up to $1.5M6d left
Other

Alumni Engagement Innovation Fund (AEIF) 2026: Strengthen U.S.–Kazakhstan Partnerships Through Alumni-Led Innovation

U.S. Mission to Kazakhstan

Up to $35K6d left
Law, Justice & Legal Services

Securing Convictions from Vetted and Special Unit Operations

U.S. Mission to Mexico

Up to $1.5M6d left
Natural Resources

2026 Atlantic Sea Scallop Research Set Aside Program

DOC NOAA - ERA Production

Amount varies9d left
Disaster Prevention & Relief

Department of the Interior (DOI), Office of Wildland Fire (OWF) - Slip-On Tanker Units

Interior Business Center

Up to $249K9d left
Arts

NEA Research Grants in the Arts, FY 2027

National Endowment for the Arts

Up to $100K9d left
Arts

NEA Research Labs, FY 2027

National Endowment for the Arts

Up to $300K9d left
Science & Technology

Innovations in Graduate Education (IGE) Program

U.S. National Science Foundation

Up to $1.0M11d left
Science & Technology

Deployed Warfighter Protection (DWFP) Program for the Protection of Deployed Military Personnel from Threats Posed by Arthropod Disease Vectors

ACC-APG-Detrick

Up to $975K11d left
Agriculture

Agriculture and Food Research Initiative Strengthening Agricultural Systems

National Institute of Food and Agriculture

Up to $10.0M12d left
Community Development

Fiscal Year (FY) 2026 AmeriCorps Seniors RSVP Competition

AmeriCorps

Amount varies12d left

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