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Government Grants in Missouri

106 state-specific grants + 3,334 federal programs available in Missouri.

Federal government grants are available to applicants in this state across all major categories including health, education, science, environment, and business development. Browse the listings below to find programs you may qualify for, and always verify eligibility on the official program website.

Business & Commerce

SSBCI Venture Capital Program — Missouri

U.S. Department of the Treasury

Amount varies
Business & Commerce

SSBCI Loan Participation Program — Missouri

U.S. Department of the Treasury

Amount varies
Science & Technology

Sbir Topic 434 Phase Ii: Development of Multilayer Strip Ion Chamber Device for the Measurement of Flash-Rt Beams Period of Performance: 9/16/24-9/15/26

Department of Health and Human Services — National Institutes of Health

Up to $2.0M
Science & Technology

Sbir Concept Award-Nanosponge Linked Dclk1 Inhibitors for the Targeted Treatment of Cholangiocarcinoma

Department of Health and Human Services — National Institutes of Health

Up to $353K
Science & Technology

Computer Vision Under Strict Security Constraints: Applications for Robotics

Department of Defense — Air Force

Up to $75K
Science & Technology

Defect Detection in Metal Additive Manufacturing

Department of Defense — Navy

Up to $140K
Science & Technology

Autonomous VTOL Fixed-Wing UAS with 8 hours Flight Time for Tactical ISR and Person Portable Logistics

Department of Defense — Air Force

Up to $75K
Science & Technology

Accelerated Target Engagement with a Droppable Payload Integration on a Rucksack Portable Fixed-Wing UAS

Department of Defense — Air Force

Up to $75K
Science & Technology

Portable Wireless Drone Charging in support of expeditionary and security missions in austere environments.

Department of Defense — Air Force

Up to $75K
Science & Technology

Edge AI Enabled Detection & Autonomous Tracking of Vehicles from a Rucksack Portable Fixed-Wing sUAS

Department of Defense — Army

Up to $150K
Science & Technology

High Temperature Oscillating Heat Pipe Transport System

National Aeronautics and Space Administration

Up to $149K
Science & Technology

Developing Pre-Consumer Waste as Low-Cost Cricket Feed for Small Farming Operations

Department of Agriculture

Up to $132K
Science & Technology

3D Printed Hypersonic Testbed

Department of Defense — Air Force

Up to $110K
Science & Technology

Lightweight Aircrew Body Armor

Department of Defense — Air Force

Up to $75K
Science & Technology

Low Profile Wind Energy Solution for Resilient AFBs and Remote Operations

Department of Defense — Air Force

Up to $110K
Science & Technology

Remote Automated Fitness Coaching for Airmen ?and Guardian Readiness and Deployability

Department of Defense — Air Force

Up to $75K
Science & Technology

IND Enabling Non-Clinical Development of E1v1.11, a Morpholino Anti-Sense Oligonucleotide for the treatment of Spinal Muscular Atrophy.

Department of Health and Human Services — National Institutes of Health

Up to $361K
Science & Technology

Development of a Novel Approach to Immunotherapy.

Department of Health and Human Services — National Institutes of Health

Up to $353K
Science & Technology

Commercial Augmentation - Air Refueling (COMAUG-AR)

Department of Defense — Air Force

Up to $75K
Science & Technology

SBIR Phase I:Creation of antimicrobial MyoMatrix for functional muscle regeneration in a porcine model of volumetric muscle loss

National Science Foundation

Up to $275K
Science & Technology

An American Story: A Literacy-Rich, Play-Based Approach to Teaching History

Department of Education — Institute of Education Sciences

Up to $250K
Science & Technology

A Platform to Identify Antifungal Compounds with Novel Action Mechanisms

Department of Health and Human Services — National Institutes of Health

Up to $300K
Science & Technology

SBIR Phase I:Directed evolution of site-specific bacterial transposase genes to alter specificity and efficiency of insertion of large DNA segments into restorable gene fusions

National Science Foundation

Up to $275K
Science & Technology

Fit for the Future: Automated Coaching & Wearable Technology for Airmen and Guardians

Department of Defense — Air Force

Up to $109K
Science & Technology

Depth-Resolved Algal Bloom Mapping at Lake Okeechobee, FL

Engineer Research and Development Center

Up to $96K1d left
Health

Small Research Grant Program for the Next Generation of Researchers in AD/ADRD Research (R03 Clinical Trial Optional)

National Institutes of Health

Up to $100K2d left
Income Security & Social Services

Support for a National Electronic Interstate Records Exchange System

Administration for Children and Families - ACYF/CB

Up to $1.6M2d left
Health

Service Area Competition - Additional Area 1

Health Resources and Services Administration

Up to $1.6M2d left
Other

International Religious Freedom Fund (I-REFF) Emergency Assistance

Bureau of Democracy Human Rights and Labor

Up to $4.9M2d left
Environment

2025 South Florida Program

Environmental Protection Agency

Up to $1.0M2d left
Science & Technology

Request for Information – Mutually Beneficial Multidisciplinary Innovation Ecosystems

Dept of the Army -- Materiel Command

Amount varies3d left
Education

Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed)

National Institutes of Health

Up to $350K5d left
Humanities

BJA FY25 Smart Reentry Demonstration Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

BJA FY25 Strengthening Community Supervision Agency Operations Program

Bureau of Justice Assistance

Up to $1.0M5d left
Law, Justice & Legal Services

OJJDP FY 2026 Attorney General Alliance Child ID Kits Invitation to Apply

Office of Juvenile Justice Delinquency Prevention

Up to $10.0M5d left
Education

Mobile Health: Technology and Outcomes in Low and Middle Income Countries (R21/R33 - Clinical Trial Optional)

National Institutes of Health

Amount varies6d left
Science & Technology

ROSES25: F.19 Collaborative Opportunities for Mentorship, Partnership and Academic Success in Science

NASA Headquarters

Amount varies6d left
Education

Next Gen STEM (NGS) NASA Aerospace Skilled Technical Workforce Hubs (NAS_Hub)

National Aeronautics and Space Administration

Up to $1.5M6d left
Other

Alumni Engagement Innovation Fund (AEIF) 2026: Strengthen U.S.–Kazakhstan Partnerships Through Alumni-Led Innovation

U.S. Mission to Kazakhstan

Up to $35K6d left
Law, Justice & Legal Services

Securing Convictions from Vetted and Special Unit Operations

U.S. Mission to Mexico

Up to $1.5M6d left
Natural Resources

2026 Atlantic Sea Scallop Research Set Aside Program

DOC NOAA - ERA Production

Amount varies9d left
Disaster Prevention & Relief

Department of the Interior (DOI), Office of Wildland Fire (OWF) - Slip-On Tanker Units

Interior Business Center

Up to $249K9d left
Arts

NEA Research Grants in the Arts, FY 2027

National Endowment for the Arts

Up to $100K9d left
Arts

NEA Research Labs, FY 2027

National Endowment for the Arts

Up to $300K9d left
Science & Technology

Innovations in Graduate Education (IGE) Program

U.S. National Science Foundation

Up to $1.0M11d left
Science & Technology

Deployed Warfighter Protection (DWFP) Program for the Protection of Deployed Military Personnel from Threats Posed by Arthropod Disease Vectors

ACC-APG-Detrick

Up to $975K11d left
Agriculture

Agriculture and Food Research Initiative Strengthening Agricultural Systems

National Institute of Food and Agriculture

Up to $10.0M12d left
Community Development

Fiscal Year (FY) 2026 AmeriCorps Seniors RSVP Competition

AmeriCorps

Amount varies12d left

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