Health

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

National Institutes of Health

Opportunity #: PAR-25-026

Award Ceiling

N/A

Award Floor

N/A

Close Date

Jan 7, 2027

92 days left

Total Funding

N/A

Posted Date

Dec 5, 2024

Cost Sharing Required

Grants.gov ID

357543

Description

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will utilize a bi-phasic, milestone-driven mechanism of award where the first phase can be used to finalize required pre-trial activities such as stability, shipping studies, and site training.

Eligible Applicants

State governments; County governments; City or township governments; Special district governments; Independent school districts; Public and state-controlled institutions of higher education; Federally recognized Native American tribal governments; Public housing authorities or Indian housing authorities; Native American tribal organizations other than governments; Nonprofits with 501(c)(3) status; Nonprofits without 501(c)(3) status; Private institutions of higher education; For-profit organizations other than small businesses; Small businesses; Other applicants

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