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Science & Technology

Liver fibrosis cell-based assay platform: integrating patient-derived fibrotic liver ECM with primary stellate cells, Kupffer cells, and hepatocytes to accelerate anti-fibrotic drug development

Department of Health and Human Services — National Institutes of Health

Opportunity #: 4R44DK139877-02

Award Ceiling
$968K
Award Floor
$968K
Close Date
Aug 31, 2027
534 days left
Total Funding
$968K
Expected Awards
1
Posted Date
Sep 10, 2025
Cost Sharing Required
No
Grants.gov ID
sbir-4R44DK139877-02

Description

SBIR Phase Phase II award: "Liver fibrosis cell-based assay platform: integrating patient-derived fibrotic liver ECM with primary stellate cells, Kupffer cells, and hepatocytes to accelerate anti-fibrotic drug development" awarded to XYLYX BIO, INC. in BROOKLYN, New York. Funded by Department of Health and Human Services (National Institutes of Health). Award amount: $967,715. The SBIR/STTR programs fund innovative research and development by small businesses, with Phase I for feasibility studies and Phase II for full R&D.

Eligible Applicants

Small businesses, Women-owned businesses

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