Science & Technology

Addressing Structural Disorder and Conformational Heterogeneity in Modern Therapeutic Modalities: A Unified X-ray/Cryo-EM QM/MM Ensemble Refinement Toolkit with Enhanced Density-Driven MD

Department of Health and Human Services — National Institutes of Health

Opportunity #: 1R44GM163476-01

Award Ceiling

$254K

Award Floor

$254K

Close Date

Mar 31, 2026

16 days left

Total Funding

$254K

Expected Awards

Posted Date

Sep 30, 2025

Cost Sharing Required

Grants.gov ID

sbir-1R44GM163476-01

Description

SBIR Phase Phase I award: "Addressing Structural Disorder and Conformational Heterogeneity in Modern Therapeutic Modalities: A Unified X-ray/Cryo-EM QM/MM Ensemble Refinement Toolkit with Enhanced Density-Driven MD" awarded to QUANTUMBIO INC in STATE COLLEGE, Pennsylvania. Funded by Department of Health and Human Services (National Institutes of Health). Award amount: $254,182. The SBIR/STTR programs fund innovative research and development by small businesses, with Phase I for feasibility studies and Phase II for full R&D.

Eligible Applicants

Small businesses

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