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Science & Technology

AAV-mediated delivery of the inflammasome adapter protein, ASC, as a pro-apoptotic gene therapy for schwannoma

Department of Health and Human Services — National Institutes of Health

Opportunity #: 1R44NS145814-01

Award Ceiling
$1.3M
Award Floor
$1.3M
Close Date
Jul 31, 2027
503 days left
Total Funding
$1.3M
Expected Awards
1
Posted Date
Aug 27, 2025
Cost Sharing Required
No
Grants.gov ID
sbir-1R44NS145814-01

Description

SBIR Phase Phase II award: "AAV-mediated delivery of the inflammasome adapter protein, ASC, as a pro-apoptotic gene therapy for schwannoma" awarded to MERLIN THERAPEUTICS INC in King of Prussia, Pennsylvania. Funded by Department of Health and Human Services (National Institutes of Health). Award amount: $1,256,291. The SBIR/STTR programs fund innovative research and development by small businesses, with Phase I for feasibility studies and Phase II for full R&D.

Eligible Applicants

Small businesses, Women-owned businesses

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